Monsanto was granted a section 3 breeding registration for MON 87411, or Corn Rootworm III (CRWIII), which marked the trait’s final U.S. approval necessary to support full food, feed, and environmental authorization in the U.S.

Prior to this significant milestone, Monsanto had obtained USDA deregulation for MON 87411, which was published in the Federal Register on Oct. 27.

It would build on the current biotechnology products planted by farmers today by adding a new RNA-mediated mode of action that would not only enhance the effectiveness of controlling corn rootworm but also prolong the durability of the existing Bt technologies currently in the market for corn rootworm management. This product represents the third RNA-based technology submitted for global approvals by Monsanto, and is the first RNA-based insect control trait.

MON 87411 will be combined with other deregulated corn traits as a pyramided product named SmartStax PRO that provides both above ground and below ground pest protection, and would be the first product of its kind.

Monsanto is planning a full commercial launch by the end of the decade, pending additional regulatory approvals, including a registration submission to EPA for SmartStax® PRO as well as global approvals.

Here is the link to the MON 87411 registration notice and labeling (from the EPA’s Pesticide Product Label System):

Here are the links to the MON 87411 final decision document posted to and announced in the EPA’s Pesticide Chemical Search:,3,31,7,12,25:P3_XCHEMICAL_ID:29361 (DvSnf7 dsRNA) and,3,31,7,12,25:P3_XCHEMICAL_ID:29390 (Bt Cry3Bb1 protein).

Here is the link to the docket in that contains the MON 87411 final documents (i.e., final decision document and registration notice):!docketDetail;D=EPA-HQ-OPP-2014-0293.